Answer 3 for NRS 445 Using a quantitative research article from one of the previous topics, analyze the p-value
The topic I selected is general anesthesia versus conscious sedation. In two different articles involving these anesthesia methods, two different thrombectomies post stroke were examined. The procedures review general anesthesia versus conscious sedation for endovascular therapy in acute ischemic stroke. In one particular article by Bai et al (2021), the P-value in general anesthesia recipients for higher successful recanilazation is 0.004 with a higher risk of mean arterial pressure drop p-value of <0.01, and a p-value for pneumonia of 0.009. Finalizing the study concluded that in these cases, general anesthesia was superior over conscious sedation with no difference from conscious sedation in interventional complications, intracerebral hemorrhage or cerebral infarcts after 30 days. In another study by Feil et al, (2021), the p-value for successful re-perfusion was similar in all groups with a value of 0.149, with the conscious sedation having a lower rate of complications perioperatively with a p-value of p<0.001; in this study, it was determined that conscious sedation has advantages over general anesthesia in terms of complications, time intervals and functional outcome. Generalizability in these cases can be morbidities, age, and sex. These factors in these articles are generalizable, as they are considered variables in the studies and are independently documented as such in logistics and analysis tables.
References
Bai, X., Zhang, X., Wang, T., Feng, Y., Wang, Y., Lyu, X., … & Jiao, L. (2021). General anesthesia versus conscious sedation for endovascular therapy in acute ischemic stroke: a systematic review and meta-analysis. Journal of Clinical Neuroscience, 86, 10-17. https://www.sciencedirect.com/science/article/abs/pii/S0967586821000199
Feil, K., Herzberg, M., Dorn, F., Tiedt, S., Küpper, C., Thunstedt, D. C., … & Kellert, L. (2021). General anesthesia versus conscious sedation in mechanical thrombectomy. Journal of Stroke, 23(1), 103-112. https://synapse.koreamed.org/articles/1153911
