The NURS 6501 ENDOCRINE DISORDERS MODULE 4 discussion question is about a 77-year-old female patient brought to the hospital by her daughter with complains that have led her being diagnosed with syndrome of inappropriate antidiuretic hormone
NURS 6501 ENDOCRINE DISORDERS MODULE 4
The NURS 6501 ENDOCRINE DISORDERS MODULE 4 discussion question is about a 77-year-old female patient brought to the hospital by her daughter with complains that have led her being diagnosed with syndrome of inappropriate antidiuretic hormone. Syndrome of inappropriate antidiuretic hormone (SIADH) is a disorder characterized by the increased release of antidiuretic hormones. There is the inability to suppress the secretion of the ADH hormone leading to water toxicity. The kidneys cannot excrete excess water due to too much reabsorption, hence, hyponatremia. Patient factors contribute to the development of SIADH. One of them as seen in this case study is medications use. Some medications increase the patient’s risk of developing SIADH when used for a long time. They include drugs such as antidepressants, seizure medications, diabetes, cancer, and hypertension treatment drugs(Kim, 2022). The patient in the case study is currently using drugs such as metformin and escitalopram, which have an elevated risk of SIADH.
Predisposing Conditions
Respiratory conditions such as acute respiratory failure, tuberculosis, and pneumonia also predispose patients to developing the disorder. The patient in the case study has a history of emphysema, which could precipitate other respiratory complications associated with SIADH. Disorders of the nervous system have also been linked with the development of SIADH in some patients. Accordingly, conditions such as head injury, tumors, stroke, and meningitis carry an increased risk of SIADH because of the involvement of the brain. The patient in the case study has neuropathy due to diabetes mellitus. In addition, she is at a risk of developing diabetes-related complication such as stroke. The fact that she experienced slight confusion and stumbling at home could indicate stroke (Mentrasti et al., 2020). Therefore, additional investigations should be conducted to rule out SIADH secondary to neurological conditions such as stroke.
References
Kim, G.-H. (2022). Pathophysiology of Drug-Induced Hyponatremia. Journal of Clinical Medicine, 11(19), Article 19. https://doi.org/10.3390/jcm11195810
Mentrasti, G., Scortichini, L., Torniai, M., Giampieri, R., Morgese, F., Rinaldi, S., & Berardi, R. (2020). Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH): Optimal Management. Therapeutics and Clinical Risk Management, 16, 663–672. https://doi.org/10.2147/TCRM.S206066
